Melanotan I vs Melanotan II
Melanotan I and Melanotan II are compared here on the things that actually differ between them: what class each belongs to, what each acts on, how each is supplied and what each costs per milligram. Where the registry has no figure for one of them the row is left out rather than filled in.
Side by side
| Melanotan I | Melanotan II | |
|---|---|---|
| Class | Selective MC1R agonist | Non-selective melanocortin agonist |
| Acts on | A linear alpha-MSH analogue with greater selectivity for MC1R than MT2, so it is studied primarily for melanogenesis without the broader melanocortin effects. | A cyclic analogue of alpha-MSH acting across melanocortin receptor subtypes, studied for melanogenesis and, through MC4, appetite and arousal pathways. |
| Supplied as | Lyophilised powder or pre-filled pen. | Lyophilised powder, pre-filled pen, or nasal spray. |
| Half-life | Shorter than MT2. | Around 33 hours reported for the cyclic form. |
| Storage | 2-8 C, protected from light. | 2-8 C, protected from light. Solutions darken over time. |
| Listings | 1 | 3 |
| Price from | £50 | £15 |
What actually differs
The clearest difference is class: Melanotan I is a selective MC1R agonist, Melanotan II is a Non-selective melanocortin agonist. They are not supplied the same way. Melanotan I comes as a lyophilised powder or pre-filled pen, Melanotan II as a lyophilised powder, pre-filled pen, or nasal spray. Half-life differs as well: Shorter than MT2 for Melanotan I against Around 33 hours reported for the cyclic form for Melanotan II.
- SerenQ Melanotan-1 15mg Peptide Penout of stock£50
Quanta Pharma MT2in stock£15
Quanta Pharma MT2 10mg - Nasal Sprayin stock£20- SerenQ MT2 10mg Peptide Penin stock£35
Availability checked 2026-09-09. The product page carries live stock.